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Servings Per Container: 28 (Days)
† Daily Value (DV) not established.
Take 1 capsule prior to your workout and 1 capsule before bed, preferably on an empty stomach. Alternatively, take 2 capsules at bedtime. Best when taken one hour prior to a meal or two hours after a meal. Do not use for longer than 8 continuous weeks without taking a 4 week break.
This product is only intended to be consumed by healthy adult males 21 years of age or older. This product is not recommended for women, especially those who are pregnant or nursing. Before using this product consult with your physician if you are using any prescription or over the counter medication or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MOAI (Monoamine Oxidase Inhibitor) or any other medication. Discontinue use and consult your health care professional if you experience any adverse reaction to this product. Discontinue use 2 weeks prior to surgery. Do not exceed recommended serving. Do not use if safety seal is broken or missing. Keep out of the reach of children.
Ultra-Potent Natural Hormone Optimizer
Two years ago, Core Test stormed onto the scene and quickly became known as “the best natural hormone support on the market.” Our extensive in house research and multiple blood analysis tests indicated significant rises in testosterone in 8 weeks. Our subjects were extremely amazed at the strength and lean body mass gains, muscle density and hardness, libido boost, and sense of well-being they felt while taking Core Test. Believe it or not, after a year of tweaking the formula, we have come up with an even more potent, all natural hormone balancing supplement designed to optimize lean muscle gains! Core Nutritionals is proud to present to you Core Alpha (Core Test v2)!*
- Quality Sleep*
- Dry, Hard, Lean Gains*
- Muscle Mass and Strength*
- Increased Sense of Well-Being and Libido*
- Modulation of Estrogen, Prolactin, and Cortisol*
- Elevation in Natural Growth Hormone (GH) Levels*
- Increased Natural Testosterone, Dopamine, and LH Levels*
Unleash Your Inner Alpha Male!
Core Alpha takes the super-effective Core Test formula and makes it even better! In addition to the important ingredients found in the original Core Test and the all new Core Alpha, including 3-desoxy-7-keto-DHEA, Coleus forskohlii, and vitamin D3, Core ALPHA makes five major advances in formulation over the original:*
- Replacement of sodium DAA (D-aspartic acid) with the more potent form NMDA (N-methyl-D-aspartate).*
- Inclusion of a second anti-aromatase inhibitor (Brassaiopsis glomerulata) to further support estrogen balance.*
- Inclusion of a high dose of Mucuna pruriens seed extract (50% L-dopa) to promote increased dopamine levels (and prolactin inhibition) along with supporting LH release and potential promotion of growth hormone (GH).*
- Inclusion of a high dose of zinc (as zinc aspartate) to support healthy testosterone levels.*
- Easier dosing with just 2 capsules recommended per day.
Testosterone is the ultimate muscle building hormone. You can work out until you drop, but your muscles won’t grow without sufficient levels of this anabolic hormone. So the more circulating “test” you have, the greater the anabolic environment for increasing muscular size and strength. What if you could activate the endogenous mechanisms in your body that increase testosterone production naturally?*
That is where Core Alpha comes in. Core Alpha is an all-natural, innovative product and its ingredient are backed by numerous clinical studies demonstrating promotion of luteinizing hormone (LH), dopamine, and natural testosterone levels along with the support of healthy growth hormone (GH) levels. Core Alpha also includes powerful, all-natural DSHEA compliant anti-aromatase inhibitors, patented herbal extracts, and testosterone assisting agents to support elevated testosterone levels while controlling estrogen, prolactin, and cortisol. As with all Core Nutritional's products, Core Alpha's ingredients are properly dosed and included in a non-proprietary blend formulation so you know exactly what you are supplementing.*
Ingredient Properties and Effects
N-Methyl-D-Aspartic Acid (NMDA)
D-aspartic acid (DAA) is an amino acid that is found naturally in several endocrine glands, including the testes and pituitary. While the correlation between DAA and testosterone production has been clinically documented, research indicates several possible mechanisms for these effects. It's likely that DAA acts as a neuromodulator influencing several pathways that govern the reproductive system, particularly testosterone production. Some studies indicate that DAA's concentrated presence in the hypothalamus, pituitary, and testes identify this protein as an up-regulator of gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH), growth hormone (GH), and testosterone. Some studies have found that DAA also stimulates a protein called StAR. StAR is necessary for the cholesterol transport in the cell that is needed for testosterone production. Further, its role in modulating the sexual drive implicates DAA assists nootropic activity, supporting health levels of dopamine and serotonin. Balanced levels of dopamine and serotonin have indicated significant benefits for mood, lean mass, and libido.*
To improve on D-aspartic acid we have instead incorporated N-methyl-D-aspartate (NDMA) into the Core ALPHA formula. DAA is converted into NMDA, which is a potent stimulator of the N-methyl-D-aspartate receptor pathway. By directly stimulating this pathway, NMDA is needed only in small doses unlike DAA’s higher dose requirements. In fact, NMDA elicits its hormone releasing action at concentrations approximately 100-fold lower than DAA. Thus, at a 30 mg dose, NMDA, shows promise to support optimal balance of hormones necessary for lean body mass growth, body fat reduction, healthy sex drive, and over all sense of well-being.*
3-Desoxy, 7-Keto-DHEA (“3D7K”)
3D7K is a unique new supplement. Plain 7-keto-DHEA is well-known in the supplement market as a weight management and cortisol balancing product. Core Alpha's compound, 3- desoxy, 7-keto DHEA is a lesser known metabolite of DHEA that is already present in small amounts in the body naturally, and also acts as a cortisol balancing compound (similar to other 7-oxegenated DHEA metabolites). But more importantly, 3D7K is a powerful AI (aromatase inhibitor). The enzyme known as aromatase is responsible for converting testosterone to estrogen in the human body. Furthermore, elevated estrogen can ultimately lead to lower testosterone levels in men (through signaling the hypothalamic pituitary testicular axis (HPTA) to shut down production of GnRH and LH). By binding to aromatase in an irreversible manner (suicide inhibitor), 3D7K effectively supports healthy estrogen levels through aromatase inhibition and also helps promote healthy testosterone levels.*
Because the 3D7K in Core Alpha promotes optimal balance of estrogen and cortisol, it may also allow for healthy testosterone levels from other ingredients in Core Alpha to promote lean mass without the negative side effects of unbalanced estrogen levels. Like NMDA, this would be a potent supplement all by itself, but in combination with the other ingredients it helps make Core Alpha perhaps the most effective natural hormone optimizer on the market.*
Note: 3-desoxy, 7-keto DHEA (8R,9S,10R,13S,14S)-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-7,17-dione) is a completely natural aromatase inhibitor that complies with DSHEA regulations and does not convert to testosterone or any other banned substances (unlike other anti-estrogens pulled from the market in recent years).*
Brassaiopsis glomerulata Leaf Extract (10:1)
Brassaiopsis glomerulata is a large shrub of the Araliaceae family that occurs in south and southeast Asia. Throughout Asia, this plant is used to treat rheumatism and back pain, aid in digestion, and treat bone fractures. Additionally, some studies report Brassaiopsis glomerulata inhibits carrageenan-induced swelling of rat paws (anti-inflammatory) and also induces an antipyretic (fever reduction) effect using a rat fever model induced by beer yeast or carrageenan. Despite its many medicinal uses, the most interesting aspect of the leaves of Brassaiopsis glomerulata is their ability to reduce the activity of aromatase. Studies show that multiple components of a Brassaiopsis glomerulata leaf extract are capable of aromatase inhibition. The addition of this 10:1 extract in Core Alpha, along with the 3D7K, gives this product a one-two punch at supporting a healthy estrogen balance.*
Coleus forskohlii Root Extract (20% Forskolin)
Coleus forskohlii is another powerful ingredient that helps promote fat loss, healthy testosterone levels, and lean body mass. Forskolin generates elevated levels of 3,5 cyclic adenosine monophosphate (cAMP)—a key endocrine regulator. Testosterone production in the leydig cells is mediated by luteinizing hormone (LH) and requires cholesterol. High cAMP levels up-regulate levels of LH, and also facilitate the effective transfer of cholesterol by stimulating a protein called StAR (steroidogenic acute regulator). StAR allows for faster and more efficient creation of testosterone by improving cholesterol transport and enhancing the anabolic mediation of LH. Increased cAMP levels also affect adipose tissue where it promotes the burning of fat cells through lipolysis, providing increased energy. And because forskolin increases cAMP without needing epinephrine (adrenalin), this fat-burning energy production does not require artificial stimulants.*
Mucuna pruriens Seed Extract (50% L-Dopa)
Mucuna pruriens is one of the popular medicinal plants of India and is known to contain various beneficial nutritional compounds. The main nutrient found in Mucuna pruriens is L-dopa, which acts as a natural source of dopamine. Prolactin is a hormone released by the pituitary gland, which is believed to be the cause for libido and sexual concerns in men. Mucuna pruriens’ ability to support healthy dopamine levels may significantly reduce the release of prolactin hormone by the pituitary glands offering powerful benefits. In addition, clinical evidence suggests that Mucuna pruriens not only supports healthy growth hormone levels but also contains naturally occurring serotonin precursors to support mood, memory, and overall well-being. Clinically shown to support optimal balance of growth hormone, prolactin, serotonin and other beneficial hormones, Mucuna pruriens may also assist healthy blood sugar levels (reduction in stubborn belly fat), weight management, stress support, and overall cholesterol balance.*
Vitamin D3 (Cholecalciferol)
Vitamin D3 is an essential hormone precursor that plays a vital role in many metabolic functions, including bone health, blood glucose and insulin management, support for immune and blood pressure health, lean body mass, and weight management (belly fat). Clinical trials have even linked Vitamin D3 with an increase in overall health and well-being. Although some foods contain vitamin D, the human body generates most of its vitamin D needs from the skin through regular exposure to sunlight. Severe vitamin D deficiency is a significant and widespread problem, especially in North America. In addition to its well-known properties for supporting bone density and strength and general inflammatory response, Cholecalciferol is included in Core Alpha because studies have shown that higher levels of vitamin D in men are correlated with higher levels of circulating testosterone.*
Zinc (as Zinc Aspartate)
Zinc deficiency is prevalent throughout the entire world, including the United States. Both severe and moderate zinc deficiencies are positively correlated with lower testosterone levels in men. And while zinc deficiency has been shown to lower your testosterone levels, zinc supplementation has been correlated with an increase in testosterone levels. Clinical research indicates that zinc deficiency reduces circulating luteinizing hormone and testosterone concentrations, may lower healthy levels of aromatase (increasing estrogen levels), and modifies sex steroid hormone receptor levels, thereby contributing to unhealthy hormone balance and male sexual function. Zinc supplementation with the aspartate form can support optimal zinc absorption and hormone balance.*
- Asif AR, Ljubojevic M, Sabolic I, Shnitsar V, Metten M, Anzai N, Müller GA, Burckhardt G, Hagos Y. Regulation of steroid hormone biosynthesis enzymes and organic anion transporters by forskolin and DHEA-S treatment in adrenocortical cells. Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1351-9. Epub 2006 Jul 11.
- Assisi L, Botte V, D'Aniello A, Di Fiore MM. Enhancement of aromatase activity by D-aspartic acid in the ovary of the lizard Podarcis s. sicula. Reproduction. 2001 May;121(5):803-8.
- Badmaev, V. Majeed, M. Conte, A, Parker, J. “Diterpene Forskolin (Coleus forskohlii, Benth.): A possible new compound for reduction of body weight by increasing lean body mass” Sabinsa Corporation http://www.b5srl.com/articles/nu/2002/marapr/badmaev.htm 1/21/2004.
- Balunas MJ, Su B, Riswan S, Fong HH, Brueggemeier RW, Pezzuto JM, Kinghorn AD. Isolation and Characterization of Aromatase Inhibitors from Brassaiopsis glomerulata (Araliaceae). Phytochem Lett. 2009 Feb 19;2(1):29-33
- Barger-Lux MJ, Heaney RP, Dowell S, Chen TC, Holick MF. Vitamin D and its major metabolites: serum levels after graded oral dosing in healthy men. Osteoporos Int, 1998;8:222-230.
- Brann DW. Glutamate: A Major Excitatory Transmitter in Neuroendocrine Regulation. Neuroendocrinology. 1995 Mar; 61(3):213-25.
- André C, Berthelot A, Robert JF, Thomassin M, Guillaume YC. Testimony of the correlation between DHEA and bioavailable testosterone using a biochromatographic concept: effect of two salts. J Pharm Biomed An., 2003 Dec 4: 33(5): 911-21.
- Cannell, J. J., et. al., Athletic Performance and Vitamin D. Medicine and Science in Sports and Exercise, 2009; 41(5):1102-1110
- Ding X, Staudinger J. Induction of Drug Metabolism by Forskolin, the Role of The Pregnane X Receptor and the PKA Signal Transduction Pathway. J Pharmacol Exp Ther. 2004 Sep 30.
- Changkija S. Folk medicinal plants of the Nagas in India. Asian Folkl Stud 1999;58:205–230.
- D'Aniello A. D-Aspartic acid: an endogenous amino acid with an important neuroendocrine role. Brain Res Rev. 2007 Feb;53(2):215-34.
- D'Aniello A, Di Fiore MM, D'Aniello G, Colin FE, Lewis G, Setchell BP. Secretion of D-aspartic acid by the rat testis and its role in endocrinology of the testis and spermatogenesis. FEBS Lett. 1998 Sep 25;436(1):23-7.
- D'Aniello A, Di Cosmo A, Di Cristo C, Annunziato L, Petrucelli L, Fisher G. Involvement of D-aspartic acid in the synthesis of testosterone in rat testes. Life Sci. 1996;59(2):97-104.
- D'Aniello G, et al. The role of D-aspartic acid and N-methyl-D-aspartic acid in the regulation of prolactin release. Endocrinology. (2000)
- D'Aniello A, et al. Occurrence of D-aspartic acid and N-methyl-D-aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth hormone release. FASEB J. (2000).
- Erreger K, et al. Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors. Mol Pharmacol. (2007)
- Estienne, et al. Growth Hormone Release After N-Methyl-D,L-Aspartate in Sheep: Dose Response and Effect of an Opioid Antagonist. J. Anim. Sci. 68:3198-3203
- Farah , et al. N-Methyl-D-Aspartate Treatment Increases Circulating Adrenocorticotropin and Luteinizing Hormone in the Rat. Life Sciences, vol. 42. Pp 1725-1732, 1988.
- Michael P. Godard, Brad A. Johnson and Scott R. Richmond. Body Composition and Hormonal Adaptations Associated with Forskolin Consumption in Overweight and Obese Men. Obesity Research (2005) 13, 1335–1343; doi: 10.1038/oby.2005.162.
- Hsu C, et al. Blockage of N-methyl-D-aspartate receptors decreases testosterone levels and enhances postnatal neuronal apoptosis in the preoptic area of male rats. Neuroendocrinology. (2000)
- Hsu C, et al. Prenatal Exposure of Testosterone Prevents SDN-POA Neurons of Postnatal Male Rats. J Neurophysiol 86:2374-2380, 2001.
- Jalali GR, Roozbeh J, Mohammadzadeh A, Sharifian M, Sagheb MM, Hamidian Jahromi A, Shabani S, Ghaffarpasand F, Afshariani R. Impact of oral zinc therapy on the level of sex hormones in male patients on hemodialysis. Ren Fail. 2010 May;32(4):417-9.
- Krishnan AV, Swami S, Feldman D. Vitamin D and breast cancer: inhibition of estrogen synthesis and signaling. J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):343-8.
- Keeney DS, Mason JI. Cecil H. and Ida Green. Expression of testicular 3 beta-hydroxysteroid dehydrogenase/delta 5----4-isomerase: regulation by luteinizing hormone and forskolin in Leydig cells of adult rats. Center for Reproductive Biology Sciences, Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas 75235-9051.
- Kilic M. Effect of fatiguing bicycle exercise on thyroid hormone and testosterone levels in sedentary males supplemented with oral zinc. Neuro Endocrinol Lett. 2007 Oct;28(5):681-5.
- Kinghorn AD, Su BN, Jang DS, Chang LC, Lee D, Gu JQ, Carcache-Blanco EJ, Pawlus AD, Lee SK, Park EJ, Cuendet M, Gills JJ, Bhat K, Park HS, Mata-Greenwood E, Song LL, Jang M, Pezzuto JM. Natural inhibitors of carcinogenesis. Planta Med 2004;70:691–705.
- Kreider RB, et al. Effects of Coleus forskohlii supplementation on body composition and markers of health in sedentary overweight females. Experimental Biology 2002 Late Breaking Abstracts. LB305: 2002.
- Lamanna C, Assisi L, Botte V, Di Fiore MM. Involvement of D-Asp in P450 aromatase activity and estrogen receptors in boar testis. Amino Acids. 2007 Jan;32(1):45-51. Epub 2006 Jun 1.
- Lamanna C, Assisi L, Botte V, Di Fiore MM. Endogenous testicular D-aspartic acid regulates gonadal aromatase activity in boar. J Endocrinol Invest. 2006 Feb;29(2):141-6.
- Leamon, KB; Padgett, W; Daly, JW. "Forskolin: Unique diterpene activator of adenylate cyclase in membrane and intact cells" Proc. Natl. Acad. Sci. USA 1981,78,3363-67.
- Ashok Marwah, Padma Marwah, Henry Lardy; Ergosteroids VI. Metabolism of dehydroepiandrosterone by rat liver in vitro: a liquid chromatographic–mass spectrometric study. Journal of Chromatography B, 767 (2002) 285–299.
- Mahajan GK, et al. Efficacy of aphrodisiac plants towards improvement in semen quality and motility in infertile males. J Complement Integr Med. 2012 Feb 17;9:Article 6
- Mitsuteru Numazawa, Ayako Mutsumi, Mii Tachibana,and Kumiko Hoshi. Synthesis of Androst-5-en-7-ones and Androsta-3,5-dien-7-ones and Their Related 7-Deoxy Analogs as Conformational and Catalytic Probes for the Active Site of Aromatase. J. Med. Chem. 1994, 37, 2198-2205.
- Modi KP, Patel NM, Goyal RK. Estimation of L-dopa from Mucuna pruriens LINN and formulations containing M. pruriens by HPTLC method. Chem Pharm Bull (Tokyo). 2008 Mar;56(3):357-9.
- Nagata Y, Homma H, Matsumoto M, Imai K. Stimulation of steroidogenic acute regulatory protein (StAR) gene expression by D-aspartate in rat Leydig cells. FEBS Lett. 1999 Jul 9;454(3):317-20.
- Pampillo M, et al. The effect of D-aspartate on luteinizing hormone-releasing hormone, alpha-melanocyte-stimulating hormone, GABA and dopamine release. Neuroreport. (2002)
- Pinilla L, Tena-Sempere M, Aguilar E. Role of excitatory amino acid pathways in control of gonadotrophin secretion in adult female rats sterilized by neonatal administration of oestradiol or testosterone. J Reprod Fertil. 1998 May;113(1):53-9.
- Pilz S, Frisch S, Koertke H, Kuhn J, Dreier J, Obermayer-Pietsch B, Wehr E, Zittermann A. Effect of vitamin D supplementation on testosterone levels in men. Horm Metab Res. 2011 Mar;43(3):223-5
- Prasad AS, Mantzoros CS, Beck FW, Hess JW, Brewer GJ. Zinc status and serum testosterone levels of healthy adults. Nutrition. 1996 May;12(5):344-8.
- Schubert K, Wehrberger K, Hobe G. Androsta-3,5-diene-7,17-dione: isolation from urine and formation from 7-keto-dehydro-epiandrosterone sulphate under various conditions of hydrolysis. Endocrinol Exp. 1971 Dec;5(4):205-10.
- Shafiei Neek L, Gaeini AA, Choobineh S. Effect of zinc and selenium supplementation on serum testosterone and plasma lactate in cyclist after an exhaustive exercise bout. Biol Trace Elem Res. 2011 Dec;144(1-3):454-62. doi: 10.1007/s12011-011-9138-2. Epub 2011 Jul 9.
- Shen Y, Zeng N, Jia M, Zhang Y, Wei Y, Ma Y. Experimental studies on anti-inflammatory, antipyretic and diuretic effects of several species of Tongcao and Xiao-tongcao. Zhongguo Zhongyao Zazhi 1998;23:687–690.
- Shukla KK, Mahdi AA, Ahmad MK, Shankhwar SN, Rajender S, Jaiswar SP. Mucuna pruriens improves male fertility by its action on the hypothalamus-pituitary-gonadal axis. Fertil Steril. 2009 Dec;92(6):1934-40.
- Suresh S, Prakash S. Effect of Mucuna pruriens (Linn.) on sexual behavior and sperm parameters in streptozotocin-induced diabetic male rat. J Sex Med. 2012 Dec;9(12):3066-78.
- Suresh S, Prithiviraj E, Lakshmi NV, Ganesh MK, Ganesh L, Prakash S. Effect of Mucuna pruriens (Linn.) on mitochondrial dysfunction and DNA damage in epididymal sperm of streptozotocin induced diabetic rat. J Ethnopharmacol. 2013 Jan 9;145(1):32-41.
- Topo E, Soricelli A, D'Aniello A, Ronsini S, D'Aniello G. The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats. Reprod Biol Endocrinol. 2009 Oct 27;7:120.
- Van Kiem P, Dat NT, Van Minh C, Lee JJ, Kim YH. Lupane triterpenes from the leaves of Brassaiopsis glomerulata. Arch Pharm Res 2003;26:594–596.
- Vecchio M, Navaneethan SD, Johnson DW, Lucisano G, Graziano G, Querques M, Saglimbene V, Ruospo M, Bonifati C, Jannini EA, Strippoli GF.
- Treatment options for sexual dysfunction in patients with chronic kidney disease: a systematic review of randomized controlled trials. Clin J Am Soc Nephrol. 2010 Jun;5(6):985-95.
- Wahab F, Zaman WU, Shahab M. Differential response of the primate HPG axis to N-methyl-D, L-aspartate, but not to Kisspeptin challenge under euglycemic and hypoglycemic conditions. Horm Metab Res. 2012 Jun;44(6):451-7.
- Wehr, E., et al. Association of vitamin D status with serum androgen levels in men. Clinical Endocrinology, December 2009; DOI: 10.1111