Nitric oxide information, FAQ and product listing page. This page contains everything you need to know about nitric oxide.
Nitric oxide (NO) is an important signaling molecule that acts in many tissues to regulate a diverse range of physiological and cellular processes. It's role was first discovered by several groups who were attempting to identify the agent responsible for promoting blood vessel relaxation and regulating vascular tone.
This agent was termed endothelium-derived relaxing factor (EDRF), and was initially assumed to be a protein like most other signaling molecules. The discovery that EDRF was in fact nitric oxide - a highly reactive gas - has led to an explosion of interest in this field, resulted in over 60,000 papers published in the last ten years and won the Nobel prize in 1998.
Nitric oxide has now been demonstrated to play a role in a variety of biological processes including neurotransmission, immune defense, the regulation of cell death and cell motility.
Nitric oxide has now become an extremely popular bodybuilding supplement. Nitric oxide is the muscle's "cell-signaling" molecule responsible for blood flow (hemodilation), oxygen delivery, glucose uptake, muscle velocity, power output, and muscle growth.
Taking nitric oxide supplements has been shown to increase blood flow to the muscles. This is perfect for bodybuilders, who need the maximum amount of nutrients to be delivered to the muscles when they’re under stress. Many users of nitric oxide also report an increased “pump” during training when supplementing with nitric oxide.
Nitric oxide also affects the endocrine system. It affects the release of the gonadotroptin releasing hormone, as well as the release of adrenaline from the adrenal medulla.
The main ingredient of nitric oxide supplements is the amino acid arginine. Taking too much arginine may lead to a feeling of tiredness or weakness, diarrhea and nausea. No clear dosage guidelines have been set for supplementing with arginine, so you must assess your own tolerance levels.
Here's how you assess your tolerance: You take a small dosage for 1 week, assess the effects and results, then adjust your dosage accordingly. Using this method will minimize side effects and help you to find your optimal dose. Each nitric oxide supplement comes with clear instructions about dosages.
Nitric oxide has been using in bodybuilding supplements since 1996. It’s available in both pill and powder form. Pure nitric oxide is usually found in pill form. Pre-workout nitric oxide based products have now become very popular. These products contain nitric oxide as well as vitamins, stimulants, creatine and vitamins. These new nitric oxide powders are now the most popular way to take NO2.
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Vassive-NO
Vassive-NO provides the pre-workout tools for ultimate pumps, increased mental focus, and greater muscle endurance. Get the most out of your workouts with Vassive-NO! |
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DHEA-100
AST Sports Science DHEA-100 comes in potent 100mg capsules. |
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Ultimate DHEA
Ultimate Nutrition DHEA is pure DHEA supplement available in 50mg & 100mg capsules! |
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NO2XL Capsules
Muscle Gauge Nutrition's advanced pre-workout NO2 formula is designed to get you pumped and focused for an intense workout! |
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NaNO Vapor
NaNO Vapor is MuscleTech's ultimate pre-workout formula! Just one hit of NaNO Vapor and you’ll feel focused, energized, and ready for an intense workout. |
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NaNOX9
NaNOX9 is a unique ultra-fast acting nitric oxide injection system. The new naNOX9 Hardcore is the first and only product on the market to initiate rapid compound hyper-diffusion in just nine seconds, creating faster, more powerful, muscle-flooding pumps. |
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Shock Therapy
Shock therapy is a pre-workout booster designed to give you energy and incredible muscle pumps. The nitric oxide (NO) activators, creatine and stimulants in this formula will energize you while helping to make you look more vascular and gain size. |
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SuperPump 250
Gaspari Nutrition's SuperPump 250 is a pre-workout nitric oxide formula that has been developed through extensive research and has been shown in independent laboratory testing to promote explosive increases in lean mass and in your first workout. |
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Novedex XT
Novedex XT is a natural testosterone booster.It increases testosterone by stimulating the pituitary gland to release leutenizing hormone. It is also an anti-aromatase which keeps circulating testosterone from converting to estrogen in the body. |
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VasoCharge
VasoCharge is a potent pre-workout supplement that contains synergistic ingredients that work together to take the results you will see to the next level and beyond. VasoCharge is formulated to allow you to increase the intensity of your workouts. |
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NO Shotgun
No-Shotgun™ stimulates episodes of physical intensity to encourage insane muscle pumps that can lead to muscle growth. The biochemical and physiological response to NO-SHOTGUN™ when joined with intense resistance training causes extra muscle growth. |
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White Flood
White Flood is a cutting edge pre-workout nitric oxide formula that will rev you up for lifting and cardio like none other. Not only will you experience out of this world pumps, but loads of extra energy and true muscle building potential. |
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Prolab Horny Goat Weed
Prolab's Horny Goat Weed is an exciting new formulation offering a proprietary blend of all-natural ingredients. |
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NO-Xplode
NO-Xplode is BSN’s #1 selling extreme pre-training energy and performance igniter. From the very first serving you will experience heightened physical and mental energy, muscle-expanding pumps, unmatched strength and stamina. |
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Nitrix
NITRIX® is what’s called an a.m. to p.m. vaso-muscular dilator. This product does its job by expanding your blood vessels, which acts to increase blood flow, oxygen and nutrient delivery to your muscle cells. |
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NO2XL
Muscle Gauge Nutrition's advanced pre-workout NO2 formula is designed to get you pumped and focused for an intense workout! |
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Fast Twitch
CytoSport Fast Twitch is a power workout drink engineered to give users explosive strength performance and fuel fast twitch (type II) fibers. It helps to boost nitric oxide levels for total body pumps to help you protect lean muscle mass. |
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Fast Twitch Caffeine Free
CytoSport Fast Twitch Caffeine Free is a power workout drink engineered to give users explosive strength performance and fuel fast twitch (type II) fibers, without the use of caffeine. |
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XPand
Xpand Nitric Oxide Reactor is the latest technology fusing A-AKG and Tri-Creatine Malate with the most hardcore muscle volumizers available to give serious bodybuilders the massive pumps they are sweating for! |
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Axis Labs NE2
Axis Labs NE2 is a nitric oxide booster made with arginine ethyl ester! Arginine ethyl ester is better absorbing that regular L-Arginine. Axis Labs NE2 is on sale now at Muscle and Strength! |
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Axis Labs HemodrauliX
Axis Labs HemodrauliX is a powerful nitric oxide supplement! Learn how HemodrauliX can give you massive pumps in the gym! HemodrauliX is on sale now at Muscle and Strength! |
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Hot-Rox Extreme
Hot-Rox Extreme provides 5x faster fat loss than diet and exercise alone! This potent fat burner contains Carbolin 19 and yohimbine HCl, plus a fat burning compound only found in Hot-Rox! |
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Horny Goat Weed Extract
NOW Foods Horny Goat Weed Extract is standardized to 10% Icariin and is combined with Maca, another vitality herb. Each dose of NOW Horny Goat Weed Extract delivers a massive 750mg of Horny Goat Weed and 150mg of Maca. |
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Activate Xtreme
Activate Xtreme is the pinnacle of testosterone enhancement in the sports nutrition industry. Not only does Activate Xtreme rapidly increase free testosterone, it also provides total testosterone enhancement, adaptogenic & support estrogenic control! |
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PlasmaJet
PlasmaJet is the most intense and effective nitric oxide boosting product ever seen or sold in the sports supplement industry. PlasmaJet Will take your physique to new heights! |
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Smash Fully Loaded
Smash Fully Loaded is the most complete pre-workout formula ever designed to help you experience the most intense workouts of your life through increased PUMP, STRENGTH, ENDURANCE, ENERGY and HYDRATION. |
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Black Powder
MRI Black Powder is the first and only pre-training formula to employ the powerful Nos up-regulating whey "peptide fraction" Actinos2, delivered with MRI's "Instant Release" (IR) technology. Black Powder is on sale now at Muscle and Strength! |
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NO2 Platinum
NO2 Platinum has created a revolutionary new category of muscle-builders and muscle-enhancers known as "cell-signaling hemodilators". Through mediation of the "signaling-molecule" nitric oxide (NO), NO2 Platinum increase size, strength and power output! |
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NO2 Black
NO2 Black is the first patented extended-release nitric oxide generator designed to deliver upper limit nitric oxide - all day long. MRI NO2 Black delivers 950% more nitric oxide! NO2 Black is on sale now at Muscle and Strength! |
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Dark Rage
MHP Dark Rage sets a new scientific standard of pre-workout supplementation with exclusive Technology & an amazingly powerful combination of advanced ingredients designed to take your workouts to an entirely new level of intensity! |
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Trac Extreme-NO
MHP Trac Extreme-NO is practically pure Nitric Oxide. It combines the powerful Nitric Oxide enhancing ingredients available to modern science in the most potent doses to assure that you experience your best and biggest muscle pumps! |
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Anadrox
MHP Anadrox is the world’s first supplement to combine the power of Nitric Oxide (NO) with a potent full spectrum Fat Burner to simultaneously trigger extreme muscle fiber expansion and pumps, while activating a powerful fat loss effect! |
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Ignite
Nutrex Ignite is a ground breaking pre-workout booster guaranteeing that you will never have a bad workout again. Muscle and Strength has low prices on Nutrex Ignite! |
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Niox
Nutrex Niox is a fast-acting Nitric Oxide pill designed to aid blow flow to the muscles during training. Nutrex Niox is on sale now at Muscle and Strength! |
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Anabolic Rush
Anabolic Rush is a new state of the art muscle-building and energizing formula that uses innovative breakthroughs in nutrient design and delivery technology to maximize muscle cell volume, energy and nutrient transport. |
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Jacked
USPLabs Jacked gives you the mad aggressive desire and ability to lift more weight, pump out more reps and have crazy lasting energy, along with sick muscle-engorging pumps. Jacked is on sale now at Muscle and Strength! |
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Nitric Boost
Optimum Nutrition Nitric Boost is for anyone who wishes to extend their muscle pump, signal muscle growth, speed recovery, increase their strength, stamina and sexual vigor. |
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Xpand Energized Caplets
Dymatize Energized Xpand™ caplets use a Rapid Release technology designed to deliver a signal to your muscles to grow and recover! |
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Professional Strength N.O. Fury
Six Star Muscle Professional Strength N.O. Fury is a scientifically engineered, state-of-the-art pre-workout nitric oxide formula that is designed to deliver the most overwhelming surge of nutrient-rich, muscle building blood for maximum anabolism. |
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Professional Strength Nitric Oxide Overdrive
Six Star Nitric Oxide Overdrive is a cutting-edge nitric oxide formula that's scientifically engineered for serious bodybuilders to rapidly flood their muscles with skin-stretching hardcore pumps! |
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N.O. PlasmaCore
N.O. PlasmaCore is the hardest hitting anabolic nitric oxide formula ever made and is scientifically designed to force an unrivaled anabolic, neuro-thermogenic and vaso-reactive training experience. |
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Cytonox
CytoNox is an extremely powerful pre-workout nitric oxide formula that produces maximum vasodilation, rapid muscle expansion, instant energy and focus, relentless increases in strength and extreme skin-splitting pumps. |
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Amped ECN
Met-Rx Amped ECN takes sports nutrition supplementation to a new dimension by combining proprietary formulations to support extreme energy and nutrient circulation to the cell. |
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Altered State
Altered State is a pro-competition strength nitric oxide formula designed to force-feed your muscles anabolic factors for extremely fast recovery and growth and quickly trigger vaso-muscular pumps |
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PreSurge
PreSurge by Athletic Edge Nutrition primes and fuels muscle growth, increase nitric oxide synthesis, maximizes blood flow and increases muscle fullness and hardness. |
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Monster Stack
The Monster Stack from CytoSport is designed for serious lifters who want to pack on size and lean muscle! |
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Halodrol Liquigels
Halodrol Liquigels is the next generation multi-faceted approach to maximal muscle hyperplastic catalysm! |
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Reversitol
iForce Reversitol – was designed with Optimal Hormone Regulation in mind. All hardcore athletes have felt the side effects of hormonal stress, resulting in declined performance, loss of muscle gains, and weakened intensity. |
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Estrogenex
Estrogenex is a nutritional supplement designed to normalize all hormone levels, yielding a wide spectrum of health benefits. |
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White Blood
Controlled Labs White Blood is the most complete nitric oxide and transport enhancing formula around! |
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Tribex
Biotest Tribex contains a high quality, potent Testosterone-boosting compound! |
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Basic Fat Loss Stack
The basic fat loss stack is designed for those looking to shed the fat without breaking the bank! |
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Lean Body Women's Stack
The Lean Body Women's Stack is made up of Whey Sensible, Trim Fat and EstraCort and has been designed not only to support fat loss, but to maintain and build lean muscle. |
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Formadrol Extreme XL
Formadrol Extreme ups your Testosterone levels, blocks Estrogen conversion and helps you create your own Testosterone, naturally. |
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T-911
T-911 is daily testosterone support that blocks estrogen and keeps your natural testosterone levels as high as naturally possible. |
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Hemo-Rage Black
Nutrex HemoRage, the meanest and cruelest pre-workout supplement this world has ever seen. |
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Eponox
Eponox is a next generation scientific bodybuilding breakthrough that takes vaso-muscular perpetual pumps to a whole new level with potent EPO blood building technology. |
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Xpand Xtreme Pump + Free Shaker
Dymatize Xpand Xtreme Pump generates heart-pounding, blood-pumping intensity that will take your training to the next level. |
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Tribex Gold
Biotest Tribex Gold contains a high quality, potent Testosterone-boosting compound!* |
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ReCharge
ReCharge will give you longer lasting muscle pumps, more vascularity, and more strength than you have experienced with any other supplement. |
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Super Charge Xtreme N.O.
Labrada SuperCharge Xtreme N.O. gives you energy, pump, power, and endurance with the very first dose! |
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Alpha Male
Biotest Alpha Male is an extra-strength hybrid of Biotest Tribex and Red Kat, made even more potent by Biotest's Nano-Dispersion Technology. |
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**SALE** ArimaDex - Buy 1 Get 1 Free
ArimaDex is a proprietary blend of 7 ingredients including an estrogen blocker and Resveratrol, that have all been shown to increase or maintain testosterone levels. |
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No-Xplode NT
No-Xplode NT is the next evolution of BSN's #1-selling extreme pre-training energy and performance igniter. |
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N-Gorge
ALRI N-Gorge combines powerful performance boosting, muscle-building substances in a single formula! N-Gorge is on sale now! |
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**SALE** DHEA 25 - Buy 1 Get 1 Free
Youth Addict introduces DHEA25. For women and men, age 40 and better, this supplement is designed in the optimal dosage to restore DHEA levels to those of your youth. |
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Epozine-O2 NT
>Epozine-O2 NT is BSN's revolutionary anabolic mediator & ergogenic plasma volumizer. Designed to promote superior physical performance & endurance, blood-volumizing plasma expansion, and significantly greater increases in lean muscle mass |
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