Alpha-T2

ALPHA-T2 is a clean jitter free blend of three POWERFUL and pure ingredients that are combined at perfect doses. Whether you are trying to drop weight fast or in the middle of a lean recomp phase, ALPHA-T2 belongs in your supplement regimen!

PES didn’t jam as many ingredients at unknown doses into every capsule as we could. We didn’t stuff it full of caffeine to make you think that the more jitters and crash you have means the more weight you are losing. Our products are formulated off of science and the amount of each ingredient is the full and effective dose.

• Targeted Fat Destroyer
• Clean Fat Burning All Day Long
• Increase Metabolism and Thyroid Output
• Full Body Fat Loss
• Super Thermogenic
• Extremely Versatile and Stackable
• PURE Powerful Ingredients

Get Educated on the Alpha-T2 Ingredients

Alpha-T2 is the first product that can effectively:

• Target Fat Loss
• Provide Full Body Fat Loss
• Combine multiple fat loss pathways in the body for an even greater effect – synergy at its finest
• Give powerful fat loss without any caffeine crash and jitters

Alpha-T2 contains pure Rauwolscine HCl, also known as alpha-yohimbine. Before you say “Oh damn, it’s yohimbine”?, keep on reading. Rauwolscine is VERY different than regular yohimbine. Just because they have a similar name does not mean anything as to what it does inside of your body. This new extremely superior ingredient makes yohimbine look like garbage.

Regular yohimbine is well known for nasty jitters, crash, anxiety, etc. On top of that, it hardly does anything for fat loss. Rauwolscine does NOT have the same effects and is much more powerful at burning fat then regular yohimbine! It is an essential ingredient for anyone who wants to lose weight, and we give it to you in the pure form at a full an effective dose.

Rauwolscine is the key to TARGETING fat loss in the midsection. Rauwolscine is known as an Alpha-2 adrenoceptor antagonist (Alpha-2-adrenoceptor blocker). Normally, when this receptor is active (which it’s going to be, unless you’re taking Alpha-T2), it actually slows your body’s natural ability to burn fat! By blocking the alpha-2-adrenoceptor with Rauwolscine your body will now INCREASE fat burning and DECREASE fat storage. Those evil Alpha-2 adrenoceptors are abundant in certain areas of the body; including the abdomen, the love handles, the chest, lower back, buttocks, and neck. So by taking Alpha-T2, you are TARGETING FAT LOSS in these areas!

Now, when these receptors are blocked a pathway known as the beta-adrenergic pathway is what is actually causing the increase in fat burning. So remember, alpha-2 adrenoceptors are blocked, so fat storage mechanism is decreased, and now allows the beta-adrenergic pathways to burn more fat in the midsection.

The beta-adrenergic pathway is one of the strongest fat burning pathways in the body. It burns fat over the entire body, but since we have coupled Rauwolscine in this formula there will be an even greater focus on the midsection.

Instead of stuffing Alpha-T2 full of stimulants that give nasty jitters and crash in an attempt to indirectly activate beta-adrenergic pathway, PES took these biochemical pathways a step further. We figured hey, why not find something that DIRECTLY activates this pathway by using a beta-agonist (beta-adrenergic pathway activator)? That is exactly what we did.

PES is proud to be the first producers of a new innovative and effective compliant beta-agonist, Higenamine. This ingredient directly activates the beta-adrenergic pathway. Just like Rauwolscine, we use a PURE form of Higenamine, not an extracted form.

Higenamine is a popular compound in Eastern countries and has been noted for its beta-agonistic properties. We have found in our initial testing of Higenamine that when 20-40mg of Higenamine is taken via oral route by capsule, it acts very quick and its effects last for 60-90 minutes after dosing. This makes Higenamine very effective for dosing pre-exercise to increase your fat burning during your workout or cardio, perfect for the twice per day dosing of Alpha-T2, wont keep you awake all night, and is perfect for the Alpha-T2 formula.

The 3,3'-diiodo-l-thyronine in Alpha-T2 is a fast acting metabolism booster and thermogenic. By increasing your metabolism you can shift your body to BREAK DOWN MORE FAT for energy as its primary source. 3,3'-T2 is a naturally occurring iodo-thryonine that will kick your metabolism into gear! It is the closest compliant ingredient to T3. This ingredient is the perfect cherry on top on our formula. Like our other ingredients, we use a pure form of 3,3’-T2.

There you have it. Three perfectly dosed, perfectly combined, extremely synergistic PURE ingredients designed to make you BURN FAT! There is no other product out there like Alpha-T2. No weak extracts here…PURE powerful ingredients at the EFFECTIVE doses. Not hidden in a prop blend. Not loaded with caffeine.

Users love Alpha-T2 because of its clean and effective fat burning capabilities, powerful thermogenic effects, and strong boost in metabolism. Another great benefit to this product not containing caffeine is you can stack Alpha-T2 with caffeinated products like your favorite stimulant supplements to wake you up in the morning, or your stimulant loaded preworkouts. So if you are a true caffeine junkie, yes, you can use caffeinated products with Alpha-T2 if you want.

References:

• Berlan M, Galitzky J, Riviere D, et al. Plasma catecholamine levels and lipid mobilization induced by yohimbine in obese and non-obese women. Int J Obes. 1991 May;15(5):305-315
• Galitzky J, Taouis M, Berlan M, et al. Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers. Eur J Clin Invest. 1988 Dec;18(6):587-594
• Flechtner-Mors M, Jenkinson CP, Alt A, et al. In vivo alpha(1)-adrenergic lipolytic activity in subcutaneous adipose tissue of obese subjects. J Pharmacol Exp Ther. 2002 Apr;301(1):229-233
• Sax L. Yohimbine does not affect fat distribution in men. Int J Obes. 1991 Sep;15(9):561-565
• Kucio C, Jonderko K, Piskorska D. Does yohimbine act as a slimming drug? Isr J Med Sci. 1991 Oct;27(10):550-556
• Berlin I, Stalla-Bourdillon A, Thuillier Y, et al. Lack of efficacy of yohimbine in the treatment of obesity. J Pharmacol. 1986 Jul-Sep;17(3):343-347
• Zahorska-Markiewicz B, Kucio C, et al. Adrenergic control of lipolysis and metabolic responses in obesity. Horm Metab Res. 1986 Oct;18(10):693-697
• Perry BD, U’Prichard DC. [3H]rauwolscine (alpha-yohimbine): a specific antagonist radioligand for brain alpha 2-adrenergic receptors. Eur J Pharmacol. 1981 Dec 17;76(4):461-464
• Berlan M, Le Verge R, Galitzky J, et al. Alpha 2-adrenoceptor antagonist potencies of two hydroxylated metabolites of yohimbine. Br J Pharmacol. 1993 Apr;108(4):927-932
• Calorigenic effect of diiodothyronines in the rat, Antonia Lanni, Maria Moreno, Assunta Lombardi and Fernando Goglia. Dipartimento di Fisiologia Generale ed Ambientale, Universita degli Studi di Napoli. Journal of Phy8iology (1996), 494.3, pp.831-837
• Metabolic effects of thyroid hormone derivatives. Moreno M, de Lange P, Lombardi A, Silvestri E, Lanni A, Goglia F. Dipartimento di Scienze Biologiche ed Ambientali, Università degli Studi del Sannio, Via Port’Arsa, Benevento, Italy. Thyroid. 2008 Feb;18(2):239-53.
• Chang KC, Lim JK and Park CW (1986) Synthesis of higenamine and its cardiovascular effects in rabbit: Evidence for b-adrenoceptor agonist. Kor J Pharmacol 22:96 –104
• A study on the mechanism of the yang-tonic effect of higenamine. Xiang Rong. Yi Ningyu. Xia Zongqin. PHARMACOLOGY AND CLINICS OF CHINESE MATERIA MEDICA. 1994-06
• The Chinese Journal of Clinical Pharmacology, 2007-04. Tolerability of higenamine hydrochloride in healthy volunteers. Yan-rong, Fang, Ri-yi,Yan, OUYANG, Meng, Hong-li.
• Eur J Nucl Med. 1983;8(6):233-6. Measurement of effects of the Chinese herbal medicine higenamine on left ventricular function using a cardiac probe. Liu XJ, Wagner HN Jr, Tao S. Planta Med 2009; 75(13): 1393-1399. ß2-Adrenoceptor-Mediated Tracheal Relaxation Induced by Higenamine from Nandina domestica Thunberg Muneo Tsukiyama, Takuro Ueki, Yoichi Yasuda, Hiroko Kikuchi, Tatsuhiro Akaishi, Hidenobu Okumura, Kazuho Abe.
• CHINESE PHARMACOLOGICAL BULLETIN 1995-02. The pharmacologic action of higenamine on beta-adrenergic receptors in heart of mice. XIANG Rong; XU Jiang-Tao; YI Nin-Yu; XIA Zhong-Qin
• Acta Pharmacol Sin 2008 Oct; 29 (10): 1187–1194. Identification of higenamine in Radix Aconiti Lateralis Preparata as a beta2-adrenergic receptor agonist. Gang BAI, Yang YANG, Qian SHI, Ze LIU, Qi ZHANG, Yuan-yuan ZHU
• Acta Pharmaceutica Sinica. 1982-09. EFFECTS OF dl-DEMETHYL COCLAURINE ON ß-ADRENERGIC RECEPTORS AND ADENYLATE CYCLASE IN TURKEY ERYTHROCYTE MEMBRANE. FENG Yi-pu, JIA Hong-jun, ZHANG Li-ying and ZENG Gui-yun
• An Experimental Study on Adrenergic Effect of Higenamine in Rabbit Cardiovascular System. Nam Su Kim,Chang Yee Hong,Chan Woong Pak,Jung Kyoo Lim. Korean Circ J 1986;16:1-18