I'm one of those women who respond very well to weight training. I also gain weight easily. After lifting regularly and doing long-distance cycling, I stopped it all and following grad school (8 years ago) I wound up 5'7, 240 lbs. Now I'm 165lbs, and my body fat has dropped 15%. Still have a bit of bodyfat left to lose to get to my goal (155, 23-25%)
As for "bulking up" well, I'm a lot leaner now than at 240! I am actually trying to build more muscle now since I seem to have plateaued. I just started a killer split a couple of weeks ago with a very heavy leg day. I've added .5 inch on my legs in a couple of weeks, but they actually feel harder, and already look noticeably better. I'm not emphasizing bodyfat loss right now, so I'm going to ride it out.
Some women do build more muscle than others, but I really believe the fault lies primarily with bodyfat. The bodyfat loss is slower. An overall plan with a clean diet that meets caloric needs and cardio on non-lifting days or after lifting (moderate intensity) will help.
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